Fractional Flow Reserve Measurement by Coronary Computed Tomography Angiography: A Review with Future Directions

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Based on review of available data, the Company may consider the use of noninvasive fractional flow reserve (FFR) following a positive coronary computed tomography angiography (CCTA) to guide decisions about the use of invasive coronary angiography (ICA) in patients with stable chest pain at intermediate risk of coronary artery disease (CAD i.e., suspected or presumed stable ischemic heart disea...

Coronary Computed Tomography Angiography with Selective Noninvasive Fractional Flow Reserve

Fractional flow reserve using coronary computed tomography angiography requires at least 64slice coronary computed tomography angiography and cannot be calculated when images lack sufficient quality (HeartFlow, 2013) (11% to 13% in recent studies; Koo et al, 2011; Min et al, 2012; Nakazato et al, 2013; Nørgaard et al, 2014), e.g., in obese individuals (e.g., body mass index, >35 kg/m2). The pre...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Coronary plaque quantification and fractional flow reserve by coronary computed tomography angiography identify ischaemia-causing lesions

AIMS Coronary plaque characteristics are associated with ischaemia. Differences in plaque volumes and composition may explain the discordance between coronary stenosis severity and ischaemia. We evaluated the association between coronary stenosis severity, plaque characteristics, coronary computed tomography angiography (CTA)-derived fractional flow reserve (FFRCT), and lesion-specific ischaemi...